GSS EU Science Funding Gateway

Proposals should address all of the following:

• Set up a platform supporting an innovative repurposing model with a harmonized and sustainable dimension in the EU, attracting investments and taking a position of leadership at global level. This model should integrate the scientific, methodological, financial, legal, regulatory, and intellectual property aspects of the repurposing approach.
• Provide robust and transparent selection mechanisms for prioritising already approved medicinal products or investigational products for repurposing, based on recognized unmet medical needs and sound preliminary data, and identify research priorities for the better understanding of mechanisms of action.
• Leverage, pool and share existing high quality data assets in the European repurposing landscape, also by using pharmacogenomics, in silico, and artificial intelligence (AI) approaches, innovative preclinical human in vitro cellular/multi-organ validation methods, and deliver new computational tools.
• Resolve the fragmentation and lack of ownership of the repurposing approach that greatly impedes the efficient exploitation of its potential, networking existing projects and initiatives in the field. Particular attention should be given in supporting and strengthening academic driven research.
• Devise and test a European innovation platform to enhance the collaboration among relevant European stakeholders, including academia, non-profit organisations, patients, health-care professionals, regulators, health technology assessment bodies, payers, industry, and European Research Infrastructures.

All projects funded under this topic are strongly encouraged to participate in networking and joint activities, as appropriate.  The details of these joint activities will be defined during the grant agreement preparation phase, and the Commission may take on the role of facilitator for networking and exchanges, including with relevant stakeholders, if appropriate. Ιnternational cooperation is encouraged.